Anorexia Nervosa, Bulimia Nervosa, Binge-Eating Disorder
Conditions
Interventions
None listed
Sponsors
Chiba University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Eligible participants are Japanese individuals who meet the DSM-5-TR diagnostic criteria for an eating disorder, including anorexia nervosa, bulimia nervosa, or binge-eating disorder, and who have visited the Department of Psychiatry at Chiba University Hospital. Due to practical constraints in study implementation, recruitment will primarily focus on patients with anorexia nervosa; however, patients with bulimia nervosa or binge-eating disorder may also be enrolled if they meet the eligibility criteria. Participants must be 16 to 65 years of age at the time of informed consent. Participants may also be recruited through the Internet or posted advertisements; however, eligibility will be assessed at the time of informed consent at the Department of Psychiatry of Chiba University Hospital.
Exclusion criteria
Exclusion criteria: 1. Individuals with psychiatric disorders that preceded the onset of the eating disorder and may substantially affect the assessment of eating disorder pathology, such as schizophrenia spectrum disorders, bipolar disorder, or alcohol or substance use disorders. 2. Individuals with severe physical illnesses. 3. Individuals with a past or current history of central nervous system disorders, other than the target disease, including epilepsy or head injury associated with loss of consciousness. 4. Individuals with metal objects or devices in the head region, including cochlear implants, ferromagnetic clips, deep brain stimulation devices, or vagus nerve stimulation devices, or those with cardiac pacemakers. 5. Individuals who have not been informed of their diagnosis at the time of obtaining consent. 6. Women who are pregnant, may be pregnant, or are breastfeeding. 7. Individuals whose worsening clinical condition makes it difficult for them to fully understand the study and to decide whether to participate. 8. Individuals judged by the attending physician or study physician to be unsuitable for participation in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intracortical inhibition and facilitation indices derived from motor evoked potentials recorded from the right first dorsal interosseous muscle using transcranial magnetic stimulation, including SICI, LICI, ICF, and cortical silent period | — |
Secondary
| Measure | Time frame |
|---|---|
| Behavioural measures assessed using response inhibition tasks, and clinical assessment measures including the severity of eating disorder symptoms | — |
Countries
Japan
Contacts
Public ContactYusuke Sudo
Chiba University Center for Forensic Mental Health Division of Clinical Neuroscience
Outcome results
None listed