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A Study of the Utility and Safety of Staging Laparoscopy Before Preoperative Chemotherapy in Patients with Pancreatic Cancer Without Distant Metastasis on Imaging

A Single-Center Prospective Interventional Study Evaluating the Detection Rate of Occult Distant Metastasis and Safety of Staging Laparoscopy Prior to Neoadjuvant Chemotherapy in Patients with Pancreatic Cancer Without Radiological Distant Metastasis - SL-PC Study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000061741
Enrollment
200
Registered
2026-06-01
Start date
2026-09-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pancreatic ductal adenocarcinoma

Interventions

Sponsors

Kobe University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.Age 18 years or more. 2.Patients with histologically confirmed pancreatic cancer or with a clinical diagnosis strongly suggestive of pancreatic cancer. 3.Patients with resectable or borderline resectable pancreatic cancer without evidence of distant metastasis on standard imaging assessments, including contrast-enhanced computed tomography (CT), magnetic resonance imaging (MRI), and/or fluorodeoxyglucose positron emission tomography (FDG-PET). 4.Patients who provide written informed consent to participate in the study.

Exclusion criteria

Exclusion criteria: 1.Patients with severe comorbidities considered to pose a high risk for general anesthesia and pneumoperitoneum. 2.Patients with known extensive intra-abdominal adhesions that are expected to preclude adequate laparoscopic visualization. 3.Patients undergoing treatment for distant metastases from another active malignancy. 4.Pregnant or breastfeeding women. 5.Patients whom the principal investigator considers unsuitable for participation in this study.

Design outcomes

Primary

MeasureTime frame
Detection rate of occult distant metastasis

Countries

Japan

Contacts

Public ContactJun Ishida

Division of Hepato-Biliary-Pancreatic Surgery, Department of Surgery, Kobe University Graduate Schoo Division of Hepato-Biliary-Pancreatic Surgery

jnishida38@gmail.com078-382-6302

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026