non-small cell lung cancer
Conditions
Interventions
None listed
Sponsors
Tohoku University Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Histologically diagnosed as non-small cell lung cancer using surgically resected specimens. (2) Meeting one of the following conditions: (a) Surgery was performed between January 2018 and December 2021, and ALK testing by IHC was conducted using surgical specimens. (b) Surgery was performed between January 2022 and December 2025, and ALK testing by the AmoyDx assay was conducted using surgical specimens.
Exclusion criteria
Exclusion criteria: (1) Cases in which the study participant (or a legally authorized representative) expressed a wish not to participate in the study. (2) Cases unable to undergo additional IHC testing because of insufficient remaining specimen material.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The number and proportion of ALK fusion positive cases identified by immunohistochemistry (IHC) among cases that were negative for all driver gene alterations by the AmoyDx assay. | — |
Secondary
| Measure | Time frame |
|---|---|
| The number and proportion of ALK fusion gene detection by the AmoyDx assay before and after changes in specimen handling procedures, etc. | — |
Countries
Japan
Contacts
Public ContactKen Onodera
Tohoku University Hospital Department of Thoracic Surgery
Outcome results
None listed