Esophageal cancer
Conditions
Interventions
Selection and Procedures: Participants are selected during their first visit to the Cancer Locomotive Syndrome Outpatient Clinic. The study follows a pre-defined observation and examination schedule.
Cancer Locomotive Management"
and routine perioperative care (early mobilization, respiratory physiotherapy, and swallowing therapy) before the introduction of the gum training. While these patients underwent standard cancer locom
Sponsors
Kagawa University Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Inclusion Criteria: Patients aged 20 years or older. Patients with esophageal cancer scheduled for surgical treatment. Patients enrolled in the study "Physical function and QOL improvement through multidisciplinary intervention for locomotive syndrome in cancer patients" (Approval No. 2025-050). Patients evaluated by a dentist as capable of performing masticatory training using gum. Patients capable of preoperative and postoperative follow-up assessments. Patients who have provided written informed consent for participation in this study.
Exclusion criteria
Exclusion criteria: Participants meeting any of the following criteria will be excluded: Patients with significant cognitive decline, persistent delirium, or psychiatric disorders that make it difficult to understand study procedures or complete assessments. Patients for whom the continuation of gum training or rehabilitation therapy is difficult due to severe postoperative complications or comorbidities. Patients with dental conditions (e.g., severe tooth loss or significant oral pain) that prevent safe gum chewing. Patients otherwise judged as inappropriate for participation by the principal investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Occlusal force measured using an impulse-type occlusal force meter (Oramo-bf). The assessment will be conducted at two time points: preoperatively and one month postoperatively. Two measurements will be taken at each session, and the maximum value will be used for analysis. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Activities of Daily Living (ADL): Functional Independence Measure (FIM) score. 2. Physical Activity: Measured using a triaxial accelerometer (OMRON HJA-750C). 3. Physical Function: Grip strength, Short Physical Performance Battery (SPPB), gait analysis (AYUMiEYE), and Locomotive Syndrome Risk Test (Loco-check). 4. Oral Function: Masticatory performance (using masticatory check gum), Oral Frailty 5-item Checklist (OF-5), tongue pressure, oral diadochokinesis (ODK), and Oral Health Assessment Tool (OHAT-J). 5. Psychological and Fatigue Status: Hospital Anxiety and Depression Scale (HADS) and Functional Assessment of Cancer Therapy-General (FACT-G) scores. 6. Nutritional Status: Body fluid volume measurement, Malnutrition Universal Screening Tool (MUST), and Global Leadership Initiative on Malnutrition (GLIM) criteria. Timing of assessment: Preoperatively and one month postoperatively. | — |
Countries
Japan
Contacts
Public ContactKazuma Matsunaga
Kagawa University Hospital Division of Rehabilitation, Department of Medical Technology
Outcome results
None listed