Angina with Non-Obstructive Coronary Arteries
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients who underwent coronary angiography, acetylcholine spasm provocation testing, and comprehensive coronary physiological assessment of the left anterior descending artery as part of the diagnostic evaluation for chest pain or angina symptoms associated with chronic coronary syndrome at Tsuchiura Kyodo General Hospital. Patients without functionally significant coronary artery stenosis, defined as FFR >0.80, are included.
Exclusion criteria
Exclusion criteria: Patients with acute coronary syndrome, those undergoing hemodialysis, those with incomplete physiological or laboratory data, and those with poor pressure waveform quality are excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome measure is the association between hematological inflammatory indices and ANOCA phenotypes, including structural CMD, functional CMD, isolated IMR elevation, vasospastic angina, and microvascular spasm. CMD endotypes are defined according to CFR and IMR, while vasospastic angina and microvascular spasm are diagnosed by acetylcholine provocation testing. | — |
Countries
Japan
Contacts
Tsuchiura Kyodo General Hospital Department of Cardiovascular Medicine