FindTrial
Sign In

Elucidating the mechanisms of meniscal degeneration and extrusion in knee osteoarthritis using RNA sequencing

Elucidating the mechanisms of meniscal degeneration and extrusion in knee osteoarthritis using RNA sequencing - Elucidating the mechanisms of meniscal degeneration and extrusion in knee osteoarthritis using RNA sequencing

Status
Active, not recruiting
Phases
Unknown
Study type
Unknown
Source
JPRN
Registry ID
JPRN-UMIN000061707
Enrollment
Unknown
Registered
2026-06-01
Start date
2026-05-27
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

knee osteoarthritis

Interventions

None listed

Sponsors

Osaka Medical and Pharmaceutical University
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Patients with osteoarthritis of the knee Age 60 to under 70. Female. Written informed consent obtained from the research participant.

Exclusion criteria

Exclusion criteria: Inflammatory joint diseases such as chronic rheumatoid arthritis and crystal-induced arthritis History of infectious arthritis Cases in which the same knee has undergone extensive meniscectomy or artificial joint replacement in the past Cases where participation in the study is deemed inappropriate due to severe systemic complications

Design outcomes

Primary

MeasureTime frame
Identification of differences in cell subset composition and gene expression profiles between the group with severe meniscal extrusion and the group with mild/no meniscal extrusion.—

Countries

Japan

Contacts

Public ContactKei Tanaka

Osaka Medical and Pharmaceutical University Orthopedic surgery

kei.tanaka@ompu.ac.jp080-6127-1030

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026