colorectal or gastric cancer receiving chemotherapy regimens including FOLFOX or XELOX.
Conditions
Interventions
Participants will perform oral rinsing with ozone nano-bubble water three times daily after tooth brushing during the first cycle of chemotherapy.
Sponsors
International University of Health and Welfare
Nanosui Company
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Participants who meet all of the following criteria will be eligible for inclusion: 1.Patients with colorectal or gastric cancer scheduled to receive chemotherapy regimens including FOLFOX or XELOX 2.Patients who are able to safely perform oral rinsing without choking or aspiration 3.Patients aged 20 years or older at the time of informed consent 4.Patients who have provided written informed consent after receiving adequate explanation using an informed consent document
Exclusion criteria
Exclusion criteria: Patients meeting any of the following criteria will be excluded: 1.Patients who are unable to safely and appropriately perform oral rinsing due to swallowing disorders, impaired consciousness, or cognitive impairment 2.Patients with a history of hypersensitivity to any component of ozonated nanobubble water 3.Patients judged by the principal investigator to be inappropriate for participation in this study for safety reasons
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of oral mucositis after chemotherapy. | — |
Secondary
| Measure | Time frame |
|---|---|
| Severity of oral mucositis and time to onset Quality of life (QOL) Taste disorder | — |
Countries
Japan
Contacts
Public ContactAmi Nishijima
International University of Health and Welfare Narita Hospital Department of Hepato-Biliary-Pancreatic and Gastrointestinal Surgery
Outcome results
None listed