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Association Between Glycemic Variability and the Risk of Glaucoma Progression in Patients with Diabetes

Association Between Glycemic Variability and the Risk of Glaucoma Progression in Patients with Diabetes - Glycemic Control and the Risk of Glaucoma Progression in Patients with Diabetes

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000061684
Enrollment
10000
Registered
2026-05-30
Start date
2026-06-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetes

Interventions

None listed

Sponsors

Nagoya University Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients aged 20 years or older with diabetes who have been prescribed insulin or sulfonylureas and have a diagnosis of glaucoma.

Exclusion criteria

Exclusion criteria: 1) Patients with glaucoma diagnoses other than those specified above Applicable diagnostic codes: H40.0, H40.2, H40.3, H40.4, H40.5, H40.6, H40.8, H40.9, H42 2) Patients with comorbid diseases that may cause severe visual impairment and influence the decision to perform surgery, or diseases that may increase the frequency of medical visits and thereby contribute to surveillance bias, including age-related macular degeneration, proliferative diabetic retinopathy, diabetic macular edema, cystoid macular edema, retinal vascular occlusion, retinal detachment, macular hole, optic neuritis, and uveitis Applicable diagnostic codes: H35.3, H34.8, H33, H35.81, H43.1, H35.34, H20, H30, H17, H46, H47 3) Patients who have previously undergone retinal photocoagulation, intravitreal injection, or vitrectomy Procedure codes: K277, K280, K282 4) Patients with a total available data period of less than 6 years, including both the landmark period and the window period 5) Patients with missing information required to ascertain the primary outcome

Design outcomes

Primary

MeasureTime frame
Performance of glaucoma surgery, defined by the medical procedure code corresponding to glaucoma-related surgery (K268)

Countries

Japan

Contacts

Public ContactAyana Suzumura

Nagoya University Hospital Ophthalmology

suzumura.ayana.t5@f.mail.nagoya-u.ac.jp0527442275

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026