Post-Endodontic Pain
Conditions
Interventions
Medicine: Ketoprofen transdermal patch A ketoprofen 30 mg transdermal patch was applied once to intact skin immediately after endodontic treatment in adult patients. The patch was replaced after 24 h
Sponsors
NIMS University, Jaipur, Rajasthan, India
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Patients aged 18 to 60 years 2.Patients diagnosed with symptomatic irreversible pulpitis or symptomatic apical periodontitis Multi-rooted teeth indicated for single-visit root canal treatment 3. Patients experiencing moderate to severe preoperative pain 4. Systemically healthy individuals 5. Patients willing to participate and comply with follow-up protocol
Exclusion criteria
Exclusion criteria: 1. Patients with a known history of hypersensitivity or adverse reactions to diclofenac, ketoprofen, or other non-steroidal anti-inflammatory drugs (NSAIDs), including reactions such as bronchospasm, shock, or urticaria, were excluded from the study. 2. Individuals with a history of active gastric or duodenal ulceration within the previous six months were not included. 3. Patients who were currently receiving NSAIDs or corticosteroid therapy during the study period were excluded. 4. Participants with a medical history of systemic conditions such as bronchial asthma, epilepsy, inflammatory bowel disease, severe hepatic or renal impairment, dengue fever, or any psychological or psychiatric disorders were not considered eligible for inclusion. 5. Pregnant and lactating women were excluded from the study. 6. Patients with a history of antibiotic use during the study period were also excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Assessment of post-endodontic pain intensity using the Visual Analog Scale (VAS) at different time intervals following root canal treatment. | — |
Secondary
| Measure | Time frame |
|---|---|
| Assessment of adverse effects, need for rescue medication, and patient acceptance of transdermal and oral analgesic therapies following endodontic treatment. | — |
Countries
Asia(except Japan)
Contacts
Public ContactCHITRA KUMARI
NIMS DENTAL COLLEGE & HOSPITAL, NIMS UNIVERSITY, RAJASTHAN, JAIPUR Conservative Dentistry & Endodontics
Outcome results
None listed