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Safety and Effectiveness of Fat Grafting as an Adjunct to Breast Reconstruction: A Multicenter Retrospective Observational Study in Japan

Safety and Effectiveness of Adjunctive Fat Grafting in Postmastectomy Breast Reconstruction: A Multicenter Retrospective Observational Study in Japan - JOPBS-HBR Retrospective Study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000061632
Enrollment
1000
Registered
2026-05-19
Start date
2026-02-24
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postmastectomy breast defect

Interventions

None listed

Sponsors

Kanto Central Hospital of the Mutual Aid Association of Public School Teachers
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Patients who meet all of the following criteria will be included: Patients who underwent postmastectomy breast reconstruction at a participating institution between January 1, 2013 and December 31, 2025. Patients who underwent implant-based or autologous breast reconstruction. Patients for whom medical record information is available regarding the use or non-use of adjunctive fat grafting and the major postoperative clinical course. Female patients aged 18 years or older at the time of surgery.

Exclusion criteria

Exclusion criteria: Patients who meet any of the following criteria will be excluded: Patients with insufficient medical record information to determine the use or non-use of adjunctive fat grafting or to evaluate the primary outcome. Patients whose procedures do not correspond to postmastectomy breast reconstruction, even if performed during the study period. Patients who refuse the use of their clinical information for this study through the opt-out process. Patients deemed unsuitable for inclusion in this study by the principal investigator or co-investigators.

Design outcomes

Primary

MeasureTime frame
The primary outcome is the incidence of postoperative complications after breast reconstruction, including complications related to the reconstructed breast, fat-grafted site, and fat-harvest site.

Countries

Japan

Contacts

Public ContactTakanobu Mashiko

Kanto Central Hospital of the Mutual Aid Association of Public School Teachers Department of Plastic Surgery

aesthetic_qp@hotmail.com09072260121

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026