Molecular, Cellular, and Spatial Analysis of Granulomas in Crohn's Disease

Molecular, Cellular, and Spatial Analysis of Granulomas in Crohn's Disease - Molecular, Cellular, and Spatial Analysis of Granulomas in Crohn's Disease

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000061595

Enrollment

Registered

2026-05-25

Start date

2026-05-25

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Crohn&#39

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who visited Kitasato University Kitasato Institute Hospital and meet all of the following criteria: 1. Patients aged 18 years or older with a diagnosis of Crohn's disease 2. Patients from whom tissue specimens have been obtained by surgical resection or endoscopic biopsy 3. Patients in whom granuloma formation has been pathologically confirmed, and whose residual tissue specimens are preserved after completion of diagnostic procedures

Exclusion criteria

Exclusion criteria: Patients who meet any of the following criteria 1. Patients from whom written informed consent cannot be obtained 2. Patients deemed unsuitable for study participation by the principal investigator

Design outcomes

Primary

Measure	Time frame
Types and localization of antigens, cellular profiles of granuloma constituents, and expression of molecules related to phagocytosis, antigen processing, and inflammatory regulation in granuloma tissues	—

Countries

Japan

Contacts

Public ContactYoshiki Morihisa

Kitasato University Kitasato Institute Hospital Gastroenterology

morihisa.yoshiki@kitasato-u.ac.jp03-3444-6161

Outcome results