Exploration of liver disease progression pathways and identification of novel biomarkers

Molecular analysis of liver disease progression and biomarker exploration using human liver samples - Molecular and biomarker exploration in liver diseases

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000061493

Enrollment

Registered

2026-05-11

Start date

2026-05-11

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Liver disease

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Human liver samples obtained from brain dead donors, consisting of transplant ineligible livers for which consent for research use was obtained, together with accompanying clinical information.

Exclusion criteria

Exclusion criteria: Samples that do not meet the quality requirements for reliable molecular analyses

Design outcomes

Primary

Measure	Time frame
Relationships between liver disease stages and molecular expression profiles, and correlation between histopathological parameters and molecular expression levels.	—

Secondary

Measure	Time frame
Variations in molecular network and stage associated expression changes of specific molecules and cellular subsets in liver disease.	—

Countries

Japan

Contacts

Public ContactLin Xie

National Institutes for Quantum Science and Technology Department of Advanced Nuclear Medicine Sciences, Institute for Quantum Medical Science

xie.lin@qst.go.jp0432064039

Outcome results