Apical Periodontitis / Radicular cyst
Conditions
Interventions
None listed
Sponsors
Tohoku University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Diagnosis: Apical periodontitis or radicular cyst (2) Disease stage: The size of the radiolucent area on cone-beam CT scans is 2 mm or greater (3) Age: 20 years or older and 70 years or younger (at the time of registration) (4) Gender: Not restricted (5) Participants who have provided written informed consent to participate in the study
Exclusion criteria
Exclusion criteria: (1) The shadow on dental X-rays or cone-beam CT scans is less than 2 mm in diameter (2) Age under 20 or 71 or over (at the time of registration) (3) Where the attending physician deems it inappropriate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Is it possible to isolate and culture human skeletal stem cell-derived progenitor cells (JASC) within CPC from approximately 100 mg of alveolar bone fragments that would normally be discarded? | — |
Secondary
| Measure | Time frame |
|---|---|
| We will use sc RNA-seq to investigate whether the JASC cells cultured in isolation within the CPC are similar to those cultured in isolation in the laboratory. | — |
Countries
Japan
Contacts
Public ContactYuya Kamano
Tohoku University Hospital Endodontics
Outcome results
None listed