A Multicenter Observational Study of Carbon-ion Radiotherapy for Squamous Cell Carcinoma of the Nasal Cavity and Paranasal Sinuses

A Multicenter Retrospective Observational Study of Carbon-ion Radiotherapy for Primary Squamous Cell Carcinoma of the Nasal Cavity and Paranasal Sinuses - Nasal & Paranasal SCC CIRT Study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000061473

Enrollment

100

Registered

2026-05-07

Start date

2026-05-08

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary Squamous Cell Carcinoma of the Nasal Cavity and Paranasal Sinuses

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Histologically confirmed primary squamous cell carcinoma of the nasal cavity or paranasal sinuses. 2) Regional lymph node status of N0-N2 at the start of carbon-ion radiotherapy. 3) No evidence of distant metastasis. 4) Deemed unsuitable for surgical resection of the primary tumor. 5) Received carbon-ion radiotherapy with curative intent. 6) At least one measurable lesion. 7) An Eastern Cooperative Oncology Group (ECOG) performance status of 0-2 at the initiation of treatment.

Exclusion criteria

Exclusion criteria: 1) Patients who declined the use of their data after public disclosure of this study (opt-out).

Design outcomes

Primary

Measure	Time frame
The primary endpoints are local control rate, progression-free survival, and overall survival.	—

Secondary

Measure	Time frame
The secondary endpoint is the grade and incidence of adverse events.	—

Countries

Japan

Contacts

Public ContactHiroaki Ikawa

National Institutes for Quantum Science and Technology QST Hospital

ikawa.hiroaki@qst.go.jp0432063306

Outcome results