Oral disease
Conditions
Interventions
After saliva collection and dental check up, participants gargle with chlorhexidine-containing mouthwash three times a day (morning, noon, and night) for about one to two weeks. They receive the sali
Sponsors
Hiroshima university
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Individuals aged 20 to 49 at the time of obtaining consent. 2. Individuals in good health who are not at risk of accidental ingestion or aspiration when using mouthwash. 3. Individuals who can provide written consent to participate in this study.
Exclusion criteria
Exclusion criteria: 1. Individuals who have been taking medications or supplements for a long period or on a continuous basis up to the time of obtaining consent. 2. Individuals at risk of hypersensitivity to mouthwash. 3. Others deemed unsuitable by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The number of oral bacteria, including S. mutans at the start of study and at the end of use of each mouthwash. | — |
Secondary
| Measure | Time frame |
|---|---|
| Plaque accumulation, periodontal condition, oral microbiota | — |
Countries
Japan
Contacts
Public ContactTatsuya Akitomo
Hiroshima university Department of Pediatric Dentistry, Graduate School of Biomedical and Health Sciences
Outcome results
None listed