Skip to content

A Study on the Effects of Heat Stress on Brain and Cognitive Function

Impact of Heat Stress on Neurovascular Coupling and Cognitive Function - HEAT-NVCC

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000061399
Enrollment
20
Registered
2026-06-01
Start date
2026-06-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Adult

Interventions

Seated resting condition Passive heating resting condition Exercise condition Heat stress exercise condition

Sponsors

National Institute of Advanced Industrial Science and Technology
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1 Individuals who are capable of providing written informed consent independently and voluntarily. 2 Individuals aged 18 to 40 years at the time of consent, with no restriction on sex. 3 Individuals who possess adequate physical capacity to engage in continuous exercise for a duration of 30 minutes.

Exclusion criteria

Exclusion criteria: 1 Individuals with a history of cardiovascular disease, psychiatric or neurological disorders, cerebrovascular disease, renal failure, or respiratory disease. 2 Individuals whose ability to exercise is limited due to underlying medical conditions. 3 Individuals with systolic blood pressure above 140 mmHg or diastolic blood pressure above 90 mmHg. 4 Individuals with a history of habitual smoking within the past year. 5 Individuals who are pregnant or who may be pregnant. MRI-Specific Exclusion Criteria 1 Individuals with an implanted cardiac pacemaker, artificial heart valve, or vascular stent. 2 Individuals with implanted intracranial aneurysm clips. 3 Individuals who are dependent on life-support devices. 4 Individuals using a cochlear implant. 5 Individuals with implanted neurostimulation devices. 6 Individuals with implanted surgical clips or ferromagnetic materials for hemostasis or electrical conduction. 7 Individuals who have undergone orthopedic treatment involving metallic pins, rods, or similar devices. 8 Individuals with severe claustrophobia. 9 Individuals with a history of severe head trauma or neurosurgical procedures. 10 Individuals with permanent tattoos, including cosmetic tattoos such as eyebrow tattoos.

Design outcomes

Primary

MeasureTime frame
The primary outcome is the effect of heat stress on brain activity, which will be primarily assessed using BOLD signals measured by fMRI.

Countries

Japan

Contacts

Public ContactTakashi Tarumi

National Institute of Advanced Industrial Science and Technology Research Strategy Headquarters, Self-Care Technology Research Center

takashi.tarumi@aist.go.jp08022167322

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026