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A study comparing total underwater colonoscopy and CO2 insufflation colonoscopy

A Prospective Comparative Study of Total Underwater Colonoscopy and CO2 Insufflation by Tandem Colonoscopy - TUC-CO2 Study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000061375
Enrollment
50
Registered
2026-05-01
Start date
2026-05-10
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal tumor

Interventions

First perform withdrawal under water immersion, then perform withdrawal using CO2 insufflation. The intervention period is defined as the time from obtaining informed consent to two weeks after the ex

Sponsors

Yamaguchi University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients undergoing inpatient treatment for colorectal tumors 2. Patients aged 18 years or older at the time of obtaining informed consent 3. No restriction on sex 4. Patients who have received sufficient explanation regarding participation in this study and have provided written informed consent of their own free will with adequate understanding

Exclusion criteria

Exclusion criteria: 1. Patients with a history of colorectal surgery(excluding appendectomy) 2. Patients with inflammatory bowel disease 3. Patients with polyposis 4. Patients with heart failure(NYHA class III or IV) 5. Patients with severe hepatic dysfunction (Child Pugh class B or C) 6. Patients with chronic renal failure undergoing hemodialysis or peritoneal dialysis 7. Pregnant patients 8. Patients deemed ineligible for this study by the investigator

Design outcomes

Primary

MeasureTime frame
polyp miss rate and adenoma miss rate

Secondary

MeasureTime frame
polyp detection rate and adenoma detection rate, withdrawal time, procedural pain assessment, sedative dosage

Countries

Japan

Contacts

Public Contactkoichi Hamabe

Yamaguchi University Department of Gastroenterology and Hepatology

khamabe@yamaguchi-u.ac.jp0836-22-2241

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026