Healthy Adults. This research aims to clarify the characteristics of physical and mental functions in individuals with a high level of "
Conditions
Interventions
None listed
Sponsors
National Institute of Advanced Industrial Science and Technology
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1: Individuals who are able to provide written informed consent to participate in the study of their own free will. 2: Individuals who are able to travel to the experimental site without using public transportation, in order to avoid contact with an unspecified number of people and reduce the risk of infectious disease exposure. 3: Individuals who are aged between 20 and 40 years at the time of obtaining informed consent. 4: Individuals whose biological sex is male, in order to minimize the potential influence of hormonal fluctuations associated with the menstrual cycle. 5: Individuals who self-report having regular sleep-wake schedules (i.e., an established rhythm of waking in the morning and sleeping at night). 6: Individuals who self-report having regular meal times. 7: Individuals with normal visual function, defined as a visual acuity of 0.7 or higher (with correction by glasses or contact lenses if necessary), in order to appropriately perceive the visual stimuli presented in the experiment. 8: Individuals with normal hearing ability that does not interfere with daily conversation, in order to appropriately perceive the auditory stimuli presented in the experiment. 9: Individuals who have no difficulty with or resistance to the attachment of electrodes for physiological signal measurements on the head, face, neck, flanks, chest, abdomen, ears, and other body sites. 10: Individuals who are able to participate while wearing clothing consisting of separate upper and lower garments, to allow the attachment of multiple electrodes to the body. 11: Individuals who have no resistance to saliva collection. 12: Individuals who are able to refrain from tooth brushing, eating or drinking, smoking, and vigorous physical activity for at least one hour prior to saliva collection. 13: Individuals who do not participate in any other experiments during the period of participation in this study.
Exclusion criteria
Exclusion criteria: 1: Individuals who are currently taking medications that may affect the activity of the central nervous system, peripheral nervous system, endocrine system, or immune system. 2: Individuals who have current diseases or a medical history of diseases affecting organs that are considered to influence the activity of the central nervous system, peripheral nervous system, endocrine system, or immune system, including the brain, heart, blood vessels, thymus, lymph nodes, bone marrow, spleen, liver, and adrenal glands. 3: Individuals with a body mass index (BMI) of 25.0 or higher. 4: Individuals with a body mass index (BMI) of 18.5 or lower.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary Outcome:Differences in endocrine activity across multiple days prior to task performance as a function of levels of well-being. Assessment Method:Participants are instructed to self-collect saliva samples 7 days, 3 days, and 1 day prior to the task performance day, on which they visit the laboratory to perform the task. Endocrine activity is assessed by measuring salivary cortisol concentrations, which serve as an index of endocrine system activity. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary Outcome 1: Differences in immune system activity across multiple days prior to task performance according to levels of well-being. Assessment Method: Participants self-collect saliva samples 7 days, 3 days, and 1 day prior to the task performance day. Immune system activity is assessed by measuring salivary interleukin-6 (IL-6) concentrations. Secondary Outcome 2: Differences in central nervous system activity during task performance according to levels of well-being. Assessment Method: Electroencephalography (EEG) is recorded on the task performance day and used as an index of central nervous system activity. Secondary Outcome 3: Differences in peripheral nervous system activity during task performance according to levels of well-being. Assessment Method: Electrocardiography and impedance cardiography are recorded on the task performance day. Heart rate and pre-ejection period are used as indices of peripheral nervous system activity. Secondary Outcome 4: Differences in endocrine system activity during task performance according to levels of well-being. Assessment Method: On the task performance day, participants self-collect saliva samples eight times. Endocrine system activity is assessed using salivary cortisol concentrations. Secondary Outcome 5: Differences in immune system activity during task performance according to levels of well-being. Assessment Method: Using the same saliva samples collected on the task performance day, salivary IL-6 concentrations are measured as indices of immune system activity. Secondary Outcome 6: Differences in mood during task performance according to levels of well-being. Assessment Method: Immediately after task completion, participants complete a self-report questionnaire assessing mood during task performance, and the obtained scores are used as indices of mood. | — |
Countries
Japan
Contacts
Public ContactMotohiro Kimura
National Institute of Advanced Industrial Science and Technology Human Informatics and Interaction Research Institute
Outcome results
None listed