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Real-World Comparison of Tirzepatide and Semaglutide in Patients with Type 2 Diabetes

A Retrospective Comparative Cohort Study of Tirzepatide and Semaglutide in Real-World Clinical Practice in Patients with Type 2 Diabetes - TIRASEMA Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000061320
Enrollment
200
Registered
2026-05-01
Start date
2026-04-19
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 diabetes mellitus

Interventions

None listed

Sponsors

Kimitsu Chuo Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients with type 2 diabetes who were receiving treatment during the study period, were considered by the treating physician to be appropriate candidates for treatment with semaglutide or tirzepatide, and provided written informed consent for study participation.

Exclusion criteria

Exclusion criteria: Patients from whom written informed consent for study participation could not be obtained

Design outcomes

Primary

MeasureTime frame
The primary outcomes are the changes from baseline to 6 months after treatment initiation in the Eating Behavior Questionnaire (EBQ) score and the Diabetes Treatment Satisfaction Questionnaire (DTSQ) score.

Countries

Japan

Contacts

Public ContactYasutaka Suzuki

Kimitsu Chuo Hospital Department of Medicine, Division of Diabetes, Endocrinology and Metabolism

ishibashi-cib@umin.net0438-36-1071

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026