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Inter-facility Variation in Palliative Sedation Practices: A Multicenter Prospective Observational Study in Japan

A Multicenter Prospective Observational Study to Evaluate Inter-facility Variation in Palliative Sedation Practices in Japan - Palliative Sedation Variation Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000061235
Enrollment
200
Registered
2026-04-13
Start date
2026-06-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Palliative sedation, terminal sedation

Interventions

None listed

Sponsors

Osaka Rosai Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Hospitalized patients in eligible wards (general wards or palliative care units) at participating institutions. Patients in whom palliative sedation is initiated for the relief of refractory suffering at the end of life. Eligibility is based on the concept of Intent plus Maintenance: sedation must be intentionally initiated for symptom relief and maintained in a sustained or repetitive manner for a certain period. Intermittent nighttime continuous midazolam may be included when it is considered sedation with maintenance. Consecutively enrolled cases during the study period at each participating site.

Exclusion criteria

Exclusion criteria: Sedation primarily administered for intensive or high-dependency care management in the ICU or HCU. Cases receiving only temporary or single-episode procedure-related or episodic sedation for tests, procedures, or interventions. Sedation not intended for palliative symptom relief. Cases lacking the minimum essential baseline information required for the study.

Design outcomes

Primary

MeasureTime frame
Whether a numeric Richmond Agitation-Sedation Scale (RASS) score is explicitly documented in the medical record from 30 to 60 minutes after the initiation of palliative sedation.

Countries

Japan

Contacts

Public ContactNoriyuki Kawabata

Osaka Rosai Hospital Department of Palliative Care

off.kawabata@gmail.com072-252-3561

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026