beta-trace protein concentrations in cerebrospinal fluid and epidural aspirates: a prospective observational study

beta-trace protein concentrations in cerebrospinal fluid and epidural aspirates: a prospective observational study - beta-trace protein concentrations in cerebrospinal fluid and epidural aspirates: a prospective observational study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000061233

Enrollment

Registered

2026-04-12

Start date

2019-11-11

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Differentiation of cerebrospinal fluid and epidural fluid

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients aged 20 to 75 years with American Society of Anesthesiologists physical status I or II who were scheduled to undergo elective surgery under general anesthesia with epidural analgesia or spinal anesthesia, and from whom epidural aspirates or cerebrospinal fluid samples could be collected for analysis.

Exclusion criteria

Exclusion criteria: Patients who did not meet the inclusion criteria, those in whom epidural aspirates or cerebrospinal fluid samples could not be obtained, and those judged by the investigators to be inappropriate for participation.

Design outcomes

Primary

Measure	Time frame
The diagnostic performance of beta-trace protein (BTP) concentration in differentiating cerebrospinal fluid (CSF) from epidural fluid, assessed by receiver operating characteristic (ROC) curve analysis (area under the curve, sensitivity, and specificity).	—

Countries

Japan

Contacts

Public ContactMisuzu Hayashi

University of the Ryukyus Hospital Department of Anesthesiology

hayashi_fggz@cs.u-ryukyu.ac.jp098-894-1301

Outcome results