Gut microbiota mediates the association between aging and cognitive function: evidence from a population-based study linking diet, Bifidobacterium, and Mini-Mental State Examination (MMSE) score

Gut microbiota mediates the association between aging and cognitive function: evidence from a population-based study linking diet, Bifidobacterium, and Mini-Mental State Examination (MMSE) score - Mediation analysis among age, MMSE, and Bifidobacterium

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000061232

Enrollment

1000

Registered

2026-04-11

Start date

2026-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

community-dwelling older adults

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Local residents aged 65 and over who can cooperate

Exclusion criteria

Exclusion criteria: Nothing in particular.

Design outcomes

Primary

Measure	Time frame
To explore gut bacteria involved in age-related cognitive decline.	—

Secondary

Measure	Time frame
To clarify the relationship between gut bacteria and diet.	—

Countries

Japan

Contacts

Public ContactYuji Naito

Kyoto Prefectural University of Medicine Department of Human Immunology and Nutrition Science

ynaito@koto.kpu-m.ac.jp075-251-5124

Outcome results