A study of axillary lymphaticovenular anastomosis for the prevention of lymphedema in patients undergoing breast cancer surgery

A clinical study of direct lymphaticovenular anastomosis in the axillary region for patients undergoing axillary lymph node dissection for breast cancer - Axillary Direct LVA Study

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000061217

Enrollment

180

Registered

2026-04-09

Start date

2026-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast cancer and lymphedema

Interventions

During axillary lymph node dissection for breast cancer, lymphaticovenular anastomosis (LVA) is additionally performed in the axillary region by anastomosing upper extremity lymphatic vessels identifi

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Female patients aged 18 years or older Patients with primary breast cancer scheduled to undergo axillary lymph node dissection based on clinical guidelines or institutional tumor board decisions Patients who have provided written informed consent for participation in this study

Exclusion criteria

Exclusion criteria: Patients with inflammatory breast cancer Patients with poor long-term prognosis Patients in whom no lymphatic vessel injury is identified intraoperatively Patients deemed inappropriate for participation by the investigator Patients who do not provide informed consen

Design outcomes

Primary

Measure	Time frame
Incidence of upper extremity lymphedema within 2 years after surgery	—

Countries

Japan

Contacts

Public ContactKahori Tsukura

Toyama University Hospital Department of Plastic and Reconstructive Surgery and Aesthetic Surgery

ktsukura73tyrd@gmail.com0764342281

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026