A Multicenter Observational Study on the Long-term Prognosis of Patients with Polycystic Kidney Disease

A Multicenter Observational Study on the Long-term Prognosis of Patients with Polycystic Kidney Disease:Japanese National Registry for long-term prognosis of ADPKD (JRP-PROG) - A Study on the Long-term Prognosis of Patients with Polycystic Kidney Disease

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000061211

Enrollment

3000

Registered

2026-04-09

Start date

2024-10-18

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Polycystic Kidney Disease

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with Autosomal Dominant Polycystic Kidney Disease (ADPKD): Patients who meet the diagnostic criteria for ADPKD as defined in the Polycystic Kidney Disease (PKD) Clinical Practice Guidelines 2020. eGFR>=16mL/min/1.73m2

Exclusion criteria

Exclusion criteria: Patients receiving kidney replacement therapy (hemodialysis, peritoneal dialysis, or post-kidney transplantation) Patients deemed unsuitable for inclusion in the study by the principal investigator for any other reason

Design outcomes

Primary

Measure	Time frame
Composite of a >=30% decline in eGFR, a >=50% decline in eGFR, or initiation of kidney replacement therapy	—

Secondary

Measure	Time frame
Rate of eGFR decline during the observation period Rate of increase in total kidney volume (TKV) Death	—

Countries

Japan

Contacts

Public ContactHiroshi Kataoka

Tokyo Women's Medical University Division of Nephrology, Department of Internal Medicine

kataoka.hiroshi@twmu.ac.jp03-3353-8111

Outcome results