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A Comparative Study of the Effectiveness of Brushing and L8020 Application in Reducing Oral Bacterial Counts in Intubated Patients: A Preliminary Study

A Comparative Study of the Effectiveness of Brushing and L8020 Application in Reducing Oral Bacterial Counts in Intubated Patients: A Preliminary Study - A Comparative Study of the Effectiveness of Brushing and L8020 Application in Reducing Oral Bacterial Counts in Intubated Patients: A Preliminary Study

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000061206
Enrollment
20
Registered
2026-04-09
Start date
2026-04-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients on endotracheal intubation

Interventions

After performing oral care, apply L8020. After performing oral care, apply tap water.

Sponsors

others
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients in the ICU who are intubated due to cerebrovascular disease, cardiovascular disease, or severe infection. 2. Patients aged 45 years or older 3. Patients for whom consent has been obtained from the patient, their family, or a surrogate decision-maker after receiving a thorough explanation and demonstrating a full understanding of the study (since the patient is intubated and consent cannot be obtained prior to intubation).

Exclusion criteria

Exclusion criteria: 1. Patients with conditions other than the target disease. 2. Patients with edentulism. 3. Patients who do not consent to participate in the study. 4. Any other patients deemed unsuitable for the study by the principal investigator or other study personnel.

Design outcomes

Primary

MeasureTime frame
oral bacterial count

Countries

Japan

Contacts

Public ContactTomofumi Naruse

Hiroshima Prefectural Hospital Dentistry and Oral Surgery

natsuaya1023@gmail.com0822541818

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026