infertility
Conditions
Interventions
None listed
Sponsors
Haruki Ladies Clinic
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Female patients who underwent in vitro fertilization and embryo transfer at our clinic Having undergone at least one ovarian stimulation cycle using follitropin delta (Rekovelle) with an antagonist protocol Having undergone at least one subsequent cycle switched to follitropin beta (Follitropin) with an antagonist protocol due to poor response to follitropin delta Oocyte retrieval date between January 1, 2025 and March 31, 2026
Exclusion criteria
Exclusion criteria: Cycles in which other gonadotropin preparations were added during follitropin delta stimulation Cycles using stimulation protocols other than the antagonist protocol (e.g., PPOS) Patients with a history of ovarian surgery that may have affected ovarian reserve Cycles in which the stimulation protocol was modified for OHSS prevention Cycles with missing data precluding analysis of the primary outcome
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of oocytes retrieved per cycle (comparison between follitropin delta and follitropin beta cycles within the same patient) | — |
Secondary
| Measure | Time frame |
|---|---|
| Number of metaphase II (MII) oocytes retrieved Number of cryopreserved blastocysts Number of good-quality cryopreserved blastocysts Blastulation rate Good-quality blastulation rate | — |
Countries
Japan
Contacts
Public ContactHiromasa Kuroda
Haruki Ladies Clinic Gynecology
Outcome results
None listed