Healthy adults (generally aged 18 years or older) without apparent iron-deficiency anemia or chronic diseases
Conditions
Interventions
None listed
Sponsors
Japan Clinical Trial Association
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Participants Healthy adults (generally aged 18 years or older) without apparent iron-deficiency anemia or chronic diseases Interventions Continuous intake of Lactococcus lactis subsp. cremoris H61 (heat-killed) Comparators Placebo or no intake Outcomes Primary outcome: Serum ferritin Secondary outcomes: Serum iron, transferrin saturation (TSAT), hemoglobin, and other iron metabolism-related parameters If direct indicators of iron absorption, such as those measured using stable isotope techniques, are reported, they will also be evaluated. Study design Randomized controlled trials (RCTs) and non-randomized intervention studies
Exclusion criteria
Exclusion criteria: Animal studies, in vitro studies, studies including only patients with specific diseases, studies using lactic acid bacteria other than H61 alone, and studies that did not report iron-related outcomes
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum ferritin level | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum iron, transferrin saturation (TSAT), hemoglobin, and other iron metabolism-related parameters. If direct indicators of iron absorption, such as those measured using stable isotope techniques, are reported, they will also be evaluated. | — |
Countries
Japan
Contacts
Public ContactTakeshi Kaneko
Japan Clinical Trial Association N/A
Outcome results
None listed