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Optimizing Initial Bolus Volume During Serratus Anterior Plane Block Catheter Placement for Programmed Intermittent Bolus Analgesia in Minimally Invasive Cardiac Surgery: A Randomized Controlled Trial

Optimizing Initial Bolus Volume During Serratus Anterior Plane Block Catheter Placement for Programmed Intermittent Bolus Analgesia in Minimally Invasive Cardiac Surgery: A Randomized Controlled Trial - Initial Bolus Optimization Study for Serratus Block with Programmed Intermittent Bolus in MICS

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000061158
Enrollment
44
Registered
2026-04-05
Start date
2026-04-05
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative pain in minimally invasive cardiac surgery

Interventions

At the end of surgery, an ultrasound-guided serratus anterior plane block was performed. A 17gauge Tuohy needle was used for needle insertion, and an initial bolus of 3 mL of 0.25% levobupivacaine was

Sponsors

Department of Anesthesiology and Critical Care Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Adult patients scheduled for elective minimally invasive cardiac surgery via right lateral thoracotomy Patients scheduled to receive continuous postoperative analgesia using a serratus anterior plane block Patients who provided written informed consent after adequate explanation of the study protocol

Exclusion criteria

Exclusion criteria: Patients with a history of allergy or hypersensitivity to local anesthetics Patients with chronic opioid use Patients with a body weight <33 kg Patients with a body mass index >30 kg/m2 Patients with a history of ipsilateral (right-sided) thoracic surgery Patients with psychiatric or neurological disorders In addition, patients who required conversion from minimally invasive cardiac surgery to open thoracotomy, or in whom catheter tip position could not be evaluated on chest radiography, were excluded from the final analysis.

Design outcomes

Primary

MeasureTime frame
Catheter tip position assessed on chest radiographs immediately after surgery, on postoperative day 1, and on postoperative day 2.

Secondary

MeasureTime frame
Postoperative pain assessed using the NRS Time required to perform the nerve block Catheter insertion length Evaluation of catheter position using ultrasound imaging Presence of complications Number of rescue analgesic administrations Total opioid consumption

Countries

Japan

Contacts

Public ContactAyano Toyama

Jichi Medical University Saitama Medical Center Department of Anesthesiology and Critical Care Medicine

honda.ayano@jichi.ac.jp048-647-2111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026