Healthy Japanese
Conditions
Interventions
Duration: 99 days Test product: Cell regeneration, Cell repair Administration: Both Cell regeneration and Cell repair are taken daily. Take four tablets of Cell regeneration 10 minutes before the fi
Sponsors
WELLCREATE Co., Ltd.
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Japanese 2. Healthy individuals 3. "Women between 30 and 40 years old whose menstrual cycle has been between 25 and 35 days in the past six months" or "Men between 35 and 55 years old"
Exclusion criteria
Exclusion criteria: Individuals who 1.are undergoing medical treatment or have a medical history of malignant tumor, heart failure, or myocardial infarction 2.have a pacemaker or an ICD 3.are currently undergoing treatment for any of the following chronic diseases: cardiac arrhythmia, liver disorder, chronic kidney disease, cerebrovascular disorder, rheumatic disease, diabetes mellitus, dyslipidemia, hypertension, or any other chronic diseases 4.are taking "Foods for Specified Health Uses" or "Foods with Functional Claims" 5.are taking or using medications or supplements 6.usually take food/beverage containing functional ingredients which may influence skin (such as GABA, isoflavones, lactic acid bacteria, bifidobacteria, EPA, DHA, astaxanthin, glucosylceramide, proteoglycans, piceatannol, lycoperosides, collagen peptide) 7.are allergic to medicines or foods related to the test product (particularly, apples) 8.have mental health issues such as depression disorder, ADHD, or other issues 9.have irregular sleeping time or habit due to work such as a late-night shift 10.live with their infants less than one year old 11.sleep with their children (1 to 6 years old) 12.live with requiring long-term care persons 13.sleep with more than one person 14.have irregular lifestyles 15.are undergoing medical treatment for chronic fatigue syndrome or menopausal syndrome 16.have been diagnosed with atopic dermatitis 17.habitually receive skincare treatment or use instruments for beauty treatment 18.drink to excess every day 19.have undergone cosmetic surgery 20.are pregnant, lactating, or planning to become pregnant during this study 21.have participated in other clinical studies within 28 days before informed consent, or plan to participate in another study during this study 22.are judged as ineligible to participate in this study by the physician
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. OSA sleep inventory MA version 2. Moisture of the skin 3. Viscoelasticity of the skin 4. Blood NAD+ 5. Skin tone 6. Microscope 7. Body composition | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Individuals who experienced adverse events 2. Individuals whose urinalysis and peripheral blood test values were within the reference range at screening but became outside the reference range after intervention 3. Body composition, urinalysis, and peripheral blood test | — |
Countries
Japan
Contacts
Public ContactNaoko Suzuki
ORTHOMEDICO Inc. R&D Department
Outcome results
None listed