Healthy young men
Conditions
Interventions
At rest and exercise intervention of 28 min (vigorous-intensity cycling exercise followed by a moderate-intensity bout)
Sponsors
Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: Healthy young men who have been engaged in high-intensity aerobic exercise and can tolerate 28 minutes of moderate to vigorous aerobic exercise.
Exclusion criteria
Exclusion criteria: 1. A history of neuropsychiatric disorders such as epilepsy, major depression, or schizophrenia. 2. Habit of smoke. 3. Contraindication for head MRI examination. 4. A history of severe drug hypersensitivity. 5. A history of cardiovascular disease. 6. Current diagnosis of internal diseases such as chronic anemia or chronic renal failure. 7. Any other reason by which the principal investigator determines to exclude from the participation for this study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Regional CBF, CMRO2 in the prefrontal cortex, blood exerkines levels (BDNF, irisin and cathepsin B etc.), mood change (measured by scaling scores) | — |
Secondary
| Measure | Time frame |
|---|---|
| Respiratory variables (minute ventilation, partial pressure of arterial carbon dioxide), circulatory dynamics (heart rate, blood pressure), participants' exercise self-efficacy, personality traits, and perceived exertion during exercise | — |
Countries
Japan
Contacts
Public ContactMikio Hiura
Tokyo Metropolitan Institute of Gerontology Research Team for Neuroimaging
Outcome results
None listed