Age-related decline in cognitive function and health maintenance in healthy older adults
Conditions
Interventions
Arm A: Non-exercise plus placebo capsule group. Participants orally take 4 placebo soft capsules daily for 12 weeks. No specific exercise program is provided, and participants continue their usual dai
Sponsors
Wakayama University
Tsuno Rice Fine Chemicals Co., Ltd.
Koyasan University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Healthy men and women aged 60 to 84 years 2. Individuals judged healthy based on a medical interview or examination by a physician 3. Individuals not using medications or supplements expected to influence the study outcomes 4. Individuals who receive a full explanation of the study, understand the study, and can provide written informed consent 5. Individuals who are able to attend the scheduled visits and undergo the required assessments 6. Individuals judged eligible for participation by a physician
Exclusion criteria
Exclusion criteria: 1. Individuals judged unsuitable for participation by a physician 2. Individuals unable to attend the scheduled visits 3. Individuals using medications or supplements expected to influence the study outcomes 4. Individuals unable to understand the study or provide written informed consent 5. Individuals not cleared for participation in the exercise component based on the pre-study medical check-up
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in cognitive function assessed by Cognitrax. The primary evaluation focuses on changes from baseline to week 12. Assessments are performed at baseline, week 6, week 12, and 6 months after the end of intake. | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in subjective cognitive status assessed by the Visual Analogue Scale (VAS), physical fitness measures, anthropometric measures, blood pressure, blood biochemical parameters, and health questionnaire outcomes will be evaluated. Blood tests are performed only at baseline and after 12 weeks. | — |
Countries
Japan
Contacts
Public ContactMitsugi Motoyama
Wakayama University Wakayama University Headquarters
Outcome results
None listed