Gastrointestinal diseases requiring upper or lower endoscopy (e.g., gastroesophageal reflux disease, atrophic gastritis, gastric cancer, colorectal cancer, colorectal polyps)
Conditions
Interventions
None listed
Sponsors
Imagawa Medical Clinic
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Consecutive participants aged >= 18 years undergoing upper gastrointestinal endoscopy (EGD) or colonoscopy (CS) under sedation at our clinic who provide written informed consent to this study.
Exclusion criteria
Exclusion criteria: Known allergy or hypersensitivity to the study drugs Poor general condition classified as ASA Physical Status Class IV or V Pregnancy or breastfeeding Severe COPD or obstructive sleep apnea; severe hepatic impairment (e.g., Child-Pugh C); chronic benzodiazepine use or tolerance; severe renal impairment (eGFR < 30 mL/min/1.73 m^2) Unable or unwilling to provide written informed consent to this study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time (minutes) from end of endoscopy to discharge readiness (first attainment of PADSS>9/10) | — |
Secondary
| Measure | Time frame |
|---|---|
| Compare sedation drug use and the frequency of sedation-related adverse events (SBP <90 mmHg,SpO2 <90%, HR <50 bpm, oxygen supplementation), including whether interventions were required. | — |
Countries
Japan
Contacts
Public ContactAtsushi Imagawa
Imagawa Medical Clinic Gastroenterology
Outcome results
None listed