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A study of surgical treatment as conversion therapy for initially unresectable biliary tract carcinoma

A study of surgical treatment as conversion therapy for initially unresectable biliary tract carcinoma - surgical treatment as conversion therapy for initially unresectable biliary tract carcinoma

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000061093
Enrollment
270
Registered
2026-03-28
Start date
2026-01-30
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

biliary tract carcinoma

Interventions

None listed

Sponsors

Tokyo Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1,Patients aged over 20 years with initially unresectable biliary tract carcinoma who underwent preoperative treatment and subsequently became eligible for surgical resection 2,Patients with available preoperative clinicophysiological data and resected clinicopathological findings

Exclusion criteria

Exclusion criteria: 1,Patients who did not have initially unresectable biliary tract carcinoma 2,Patients who declined to participate in the study

Design outcomes

Primary

MeasureTime frame
An analysis of prognostic factors based on preoperative clinicophysiological and pathological variables in patients undergoing conversion surgery.

Secondary

MeasureTime frame
1,Evaluation of the relationship between the duration of preoperative therapy and prognosis in patients undergoing conversion surgery 2,Evaluation of the relationship between preoperative treatment and prognosis in patients undergoing conversion surgery 3,Evaluation of the relationship between factors rendering the tumor initially unresectable and prognosis in patients undergoing conversion surgery 4,Evaluation of the relationship between disease-specific factors and prognosis in patients undergoing conversion surgery Exploratory endpoints: A comparative analysis will be performed between pre-treatment and preoperative clinicophysiological factors in patients undergoing conversion surgery to investigate their association with prognosis. In addition, correlations with postoperative pathological factors will be assessed.

Countries

Japan

Contacts

Public ContactRyoichi Miyamoto

Ibaraki Medical Center, Tokyo Medical University Department of Gastroenterological Surgery

miyamoto.ryoichi.7p@tokyo-med.ac.jp029-887-1161

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026