Anesthesia-related Risk Determinants of Post-Induction Hypotension in Emergency Surgery for Lower Gastrointestinal Perforation (GUARD-PIH study): A Multicenter Retrospective Observational Study

Anesthesia-related Risk Determinants of Post-Induction Hypotension in Emergency Surgery for Lower Gastrointestinal Perforation (GUARD-PIH study): A Multicenter Retrospective Observational Study - GUARD-PIH study (Gastrointestinal perforation in Urgent surgery: Anesthesia-related Risk Determinants of Post-Induction Hypotension)

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000061057

Enrollment

720

Registered

2026-03-25

Start date

2026-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

lower gastrointestinal perforation

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who underwent emergency surgery for lower gastrointestinal perforation (ascending colon to rectum) between April 1, 2022, and October 31, 2025.

Exclusion criteria

Exclusion criteria: 1) Pregnancy, 2) Refusal of data use via the opt-out process, 3) Use of mechanical circulatory support, 4) Patients already intubated upon operating room admission, 5) Presence of a permanent tracheostomy or tracheostomy, 6) Missing key variables, including anesthetic induction agents or blood pressure measurements at induction, 7) Postoperative diagnosis indicating that the perforation site was outside the lower gastrointestinal tract

Design outcomes

Primary

Measure	Time frame
Blood pressure during the 30 minutes following anesthetic induction	—

Secondary

Measure	Time frame
Heart rate during the first 30 minutes after anesthetic induction, Cardiac arrest within 30 minutes after anesthetic induction, Arterial blood gas values during anesthetic induction, Location of extubation, ICU admission, In-hospital mortality	—

Countries

Japan

Contacts

Public ContactTomoaki Yatabe

Nishichita General Hospital Emergency department

yatabe.tomoaki@katch.ne.jp0562-33-5500

Outcome results