None listed
Conditions
Interventions
Sponsors
National Institutes for Quantum Science and Technology
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1. Individuals who have the capacity to provide written informed consent for participation in this study. 2. Male participants aged 18 years or older and under 40 years at the time of consent. 3. Individuals whose habitual caffeine intake is below the recommended amount for healthy adults (<400 mg/day). 4. Individuals who have no abnormalities in sleep or general health status. 5. Individuals who, within the 3 months prior to obtaining consent, have not habitually used tobacco that could affect sleep, have not received any sleep related medical treatment, and have not engaged in shift work or experienced travel across time zones. 6. Individuals judged by a physician (investigator or sub investigator) to have no health problems.
Exclusion criteria
Exclusion criteria: 1. Individuals with a history of serious physical illness or brain disorders in the past or present. 2. Individuals with drug dependence or alcohol dependence. 3. Individuals who are ineligible for MRI examinations(e.g., those with magnetic metal in the body such as tattoos or intraocular lenses, or those with claustrophobia or fear of darkness). 4. Individuals for whom caffeine intake is contraindicated. As a criterion, the description in the package insert of caffeine tablets-such as those regarding heart disease or excessive gastric acid secretion-must be followed. 5. Any other individuals deemed inappropriate as research participants by the physician who is also a researcher.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Correlations among sleep-quality indicators under caffeine and placebo conditions (such as total sleep time, wake after sleep onset, and sleep spindle duration), brain functional connectivity derived from resting-state fMRI and task-based fMRI during attention and memory tasks, cognitive task performance, and psychological assessment scores. | — |
Countries
Japan
Contacts
Public ContactYasuka Sahara
National Institutes for Quantum Science and Technology Institute for Quantum Medical Science Dept. of Molecular Imaging and Theranostics
Outcome results
None listed