Hypopharyngeal cancer, Esophageal cancer
Conditions
Interventions
None listed
Sponsors
Kyoto University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients diagnosed with superficial cancer of the cervical esophagus or the hypopharynx extending into hypopharynegal esophageal transition zone who underwent endoscopic resection. 2. Histopathologically diagnosed squamous cell carcinoma, including high-grade intraepithelial neoplasia and severe dysplasia. 3. Negative deep resection margin in the resected specimen. 4. No clinical evidence of lymph node metastasis. 5. Availability of intraoperative endoscopic images. 6. Availability of formalin-fixed, paraffin-embedded (FFPE) tissue sections of the tumor obtained at the time of endoscopic resection.
Exclusion criteria
Exclusion criteria: 1. Presence of unresectable multiple primary cancers in the head and neck or esophageal region at the time of endoscopic resection. 2. Presence of unresectable synchronous primary cancer in other organs at the time of endoscopic resection. 3. Cases with extremely short follow-up periods or an excessive amount of missing data, making reliable analysis difficult.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Overall survival, recurrence-free survival, disease-free survival, and disease-specific survival | — |
Secondary
| Measure | Time frame |
|---|---|
| The associations of patient characteristics, disease stage, lesion-related factors, early treatment-related adverse events, post-treatment stricture, and the occurrence of metachronous multiple and synchronous cancers with survival outcomes and adverse event rates will be examined. | — |
Countries
Japan
Contacts
Public ContactYo Kishimoto
Graduate School of Medicine, Kyoto University Department of Otolaryngology-Head and Neck Surgery
Outcome results
None listed