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Morphological, radiological, and histological comparison of alveolar ridge preservation using two types of bone substitute

Morphological, radiological, and histological comparison of alveolar ridge preservation using two types of bone substitute - Morphological, radiological, and histological comparison of alveolar ridge preservation using two types of bone substitute

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000060992
Enrollment
24
Registered
2026-03-20
Start date
2026-03-19
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

molar tooth loss

Interventions

hydroxyapatite/collagen composite material octacalcium/collagen composite material

Sponsors

Nagasaki University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients aged 20 years or olde but under 90 years at the time of consent acquisition Patients seeking implant treatment in the molar region Patients who require tooth extraction at the relevant site and need ARP to prevent bone resorption The difference in alveolar bone height between buccal and lingual or palatal sides is within 5 mm Patients who have provided written consent to participate in the study

Exclusion criteria

Exclusion criteria: Patients with acute inflammation at the treatment site Smokers (10 or more cigarettes per day) Pregnant patient Patients with a history of allergy to collagen Patients with uncontrolled metabolic disorders (diabetes, osteomalacia, thyroid disease, severe liver or kidney disease) Patients who are taking long term steroid or immunosuppressive drugs for autoimmune diseases, etc Patients taking antiresorptive agents Patients undergoing radiation therapy Other patients who are not adequate to participate this study

Design outcomes

Primary

MeasureTime frame
Vertical bone formation on CBCT images 3 months after ARP

Secondary

MeasureTime frame
Bone formation volume (volume percentage relative to the extraction socket) on CBCT images 3 months after ARP Buccal bone height on CBCT images 3 months after ARP Changes in alveolar ridge volume captured using intra oral scanner 3 months after ARP Histological comparison of bone formation at the time of implant placement

Countries

Japan

Contacts

Public ContactTetsurou Odatsu

Naasaki University Department of Applied Prosthodontics

odatsu@nagasaki-u.ac.jp095-819-7688

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026