chronic kidney disease reated by dialysis
Conditions
Interventions
Outpatient maintenance dialysis patients undergoing 6-hour dialysis three times a week underwent resistance exercise and aerobic exercise using an ergometer for a total of approximately 30 minutes dur
Sponsors
Ibaraki Prefectural Central Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients who have provided written informed consent to participate in this study. Sex: no restriction (both male and female patients are eligible). Age: 20 years or older at the time of consent. Treatment setting: outpatient. Patients undergoing maintenance hemodialysis for at least 6 months since initiation of dialysis, with a dialysis duration of 6 hours or longer per session.
Exclusion criteria
Exclusion criteria: Patients who are considered to have contraindications to exercise therapy based on a cardiac exercise stress test. Patients with a history of hospitalization within the past 3 months. Patients who are judged by the attending physician to be inappropriate for participation in this study for any other reason.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in peripheral blood natural killer (NK) cell activity before and after a 90-day intervention in outpatient maintenance hemodialysis patients undergoing hemodialysis three times per week (6 hours per session), who performed approximately 30 minutes of intradialytic exercise consisting of resistance training and aerobic exercise using a cycle ergometer during each dialysis session. | — |
Secondary
| Measure | Time frame |
|---|---|
| Outpatient maintenance hemodialysis patients undergoing hemodialysis three times per week (6 hours per session) were enrolled. During each dialysis session, participants performed approximately 30 minutes of intradialytic exercise consisting of resistance training and aerobic exercise using a cycle ergometer. Immunological assessments conducted before the intervention and after 90 days included granulocyte activity, immunoglobulin levels, and natural killer (NK) cell activation receptors. Physical function was evaluated using the Short Physical Performance Battery (SPPB) and the Timed Up and Go test (TUG). Nutritional status was assessed using the Geriatric Nutritional Risk Index (GNRI) and the Nutritional Risk Index for Japanese Hemodialysis Patients (NRI-JH). Quality of life (QOL) was evaluated using the EQ-5D-5L. | — |
Countries
Japan
Contacts
Public ContactAkihisa Hattori
Ibaraki Prefectural Central Hospital Nephrology
Outcome results
None listed