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Radiographic Evaluation as a Proxy for Endoscopic Assessment of Post-ESD Clip Closure after Gastric ESD: Prospective Observational Study

Radiographic Evaluation as a Proxy for Endoscopic Assessment of Post-ESD Clip Closure after Gastric ESD: Prospective Observational Study - REPLACE-G Study

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000060952
Enrollment
50
Registered
2026-03-16
Start date
2026-03-16
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Early gastric cancer and gastric adenoma

Interventions

Abdominal X-ray examination

Sponsors

Omori Red Cross Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients with lesions suspected to be early gastric cancer or gastric adenoma based on endoscopic diagnosis. 2. Lesions in which the post-resection mucosal defect does not extend to the esophagus or the duodenum. 3. Lesions measuring less than 50 mm in diameter.

Exclusion criteria

Exclusion criteria: 1. A history of endoscopic treatment for upper gastrointestinal lesions within 28 days prior to enrollment. 2. Planned concomitant endoscopic treatment for esophageal or duodenal lesions. 3. Women who are pregnant, may be pregnant, or are breastfeeding. 4. Patients with psychiatric disorders that preclude adequate understanding of the study. 5. Patients with a history of gastric surgical resection. 6. Patients who have undergone gastric tube reconstruction. 7. Patients deemed unsuitable for participation in this study by the attending physician or the investigator.

Design outcomes

Primary

MeasureTime frame
Concordance rate of the number of clips between radiographic examination and endoscopic evaluation on postoperative Day 1 following clip closure after endoscopic submucosal dissection for early gastric cancer and gastric adenoma.

Countries

Japan

Contacts

Public ContactHideyuki Chiba

Omori Red Cross Hospital Department of Gastroenterology

h.chiba04@gmail.com03-3775-3111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026