Study on Reconstruction Methods and Reflux Symptoms After Minimally Invasive Proximal Gastrectomy for Upper Gastric and Esophagogastric Junction Cancer

Reflux Esophagitis After Reconstruction Following Minimally Invasive Proximal Gastrectomy for Upper Gastric and Esophagogastric Junction Cancer - PG-Reflux Study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000060947

Enrollment

1100

Registered

2026-03-16

Start date

2026-02-27

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Proximal gastric cancer or Siewert Type II esophagogastric junction cancer

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients with histologically confirmed pStage I-III common-type upper gastric cancer or esophagogastric junction cancer. Esophagogastric junction cancer was limited to cases up to Siewert type II that were resected and reconstructed using an abdominal approach alone. 2. Patients who underwent minimally invasive proximal gastrectomy (laparoscopic or robot-assisted) with R0 resection. 3. Age: 20 years or older at the time of surgery. 4. Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1 at the time of registration. 5. Patients within 5 years after surgery for the primary disease. 6. No restriction on sex. 7. Surgeon criteria: either the primary surgeon or the assistant must be certified by the Endoscopic Surgical Skill Qualification System of the Japan Society for Endoscopic Surgery (JSES).

Exclusion criteria

Exclusion criteria: 1. Patients judged to be inappropriate for inclusion in this study by the principal investigator or a sub-investigator. 2. Patients who underwent combined resection of other organs, except for cholecystectomy performed for cholelithiasis.

Design outcomes

Primary

Measure	Time frame
Incidence of postoperative reflux esophagitis after proximal gastrectomy for upper gastric and esophagogastric junction cancer	—

Countries

Japan

Contacts

Public ContactSho Sato

Yokohama City University Medical Center Department of Surgery, Gastroenterological Center

shosato@yokohama-cu.ac.jp0452615656

Outcome results