Esophageal Cancer, Gastric Cancer, Gastric adenoma
Conditions
Interventions
Patients with confirmed esophageal or gastric cancer will undergo endoscopic examination using a conventional esophagogastroduodenoscopy (EG-860R) combined with an AI-based image diagnostic support sy
Sponsors
The Jikei University School of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients with a current diagnosis of esophageal cancer or gastric cancer (including adenoma) who are scheduled to undergo diagnostic esophagogastroduodenoscopy at Jikei University Kashiwa Hospital or Jikei University Katsushika Medical Center. Patients who have received a full explanation of the study, have demonstrated sufficient understanding, and have provided written informed consent of their own free will to participate in the study.
Exclusion criteria
Exclusion criteria: Patients who are minors (under 20 years of age). Patients who have received chemotherapy for a malignant tumor within the past 12 months. Patients in whom biopsy cannot be performed at the time of endoscopy (e.g., due to ongoing antithrombotic therapy). Patients in whom iodine staining of the esophagus cannot be performed due to allergy or other contraindications. Patients who are deemed inappropriate for enrollment in this study by the treating physician or examining endoscopist for any other reason.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sensitivity for detecting esophageal and gastric neoplasms in the screening endoscopist group using a standard upper gastrointestinal endoscope with AI assistance compared with the expert endoscopist group using a magnifying endoscope (Sensitivity was defined as the number of esophageal squamous cell carcinomas, gastric adenomas, and gastric adenocarcinomas detected in each examination divided by the total number of these lesions identified by the referring physician and during the first and second study examinations). | — |
Secondary
| Measure | Time frame |
|---|---|
| Diagnostic accuracy for esophageal and gastric cancers (discriminative performance [sensitivity, specificity, positive predictive value, and negative predictive value], and accuracy of depth-of-invasion assessment). Analysis of lesions that were difficult to detect with each endoscopy (including lesion location, tumor type, and macroscopic size). | — |
Countries
Japan
Contacts
Public ContactJumpei Yamamoto
The Jikei University School of Medicine Department of Endoscopy
Outcome results
None listed