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Investigation of the effects of thermal stimulation on cognitive task load and brain activity

Investigation of the effects of thermal stimulation on cognitive task load and brain activity - Investigation of the effects of thermal stimulation on brain network mechanisms

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000060923
Enrollment
20
Registered
2026-03-16
Start date
2026-03-16
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Thermal stimulation will be applied during a 60-minute cognitive task session -&gt
60-minute cognitive task session without intervention 60-minute cognitive task session without intervention -&gt
Thermal stimulation will be applied during a 60-minute cognitive task session

Sponsors

Kao Corporation
Lead Sponsor

Eligibility

Sex/Gender
Male

Inclusion criteria

Inclusion criteria: 1. Males aged 20-59 who are right-handed. 2. Full-time (regular) employees working at Kao Corporation's Odawara and Sumida sites. 3. Individuals who can understand and respond to questionnaires written in Japanese.

Exclusion criteria

Exclusion criteria: 1. Individuals who do not meet the requirements for undergoing MRI measurements. 2. Individuals who are sensitive to cold. 3. Individuals who are uncomfortable with cold stimuli. 4. Individuals who find it difficult to use, or are uncomfortable using, medicated patches (topical compress/patch preparations). 5. Individuals who dislike the scent of bergamot or mint. 6. Individuals who have a strong reaction to alcohol swabs (alcohol-impregnated cotton). 7. Individuals whom the principal investigator deems unsuitable for participation for any other reason, such as noncompliance with study obligations.

Design outcomes

Primary

MeasureTime frame
Brain network connectivity measured using resting-state functional MRI before and after the fatigue task and warm and cold thermal stimulation

Secondary

MeasureTime frame
Mean response (answer) time and the number of incorrect responses (errors) for each cognitive task

Countries

Japan

Contacts

Public ContactHiroaki Motohashi

Kao Corporation Human Healthcare Research Lab.

motohashi.hiroaki@kao.com+81-3-5630-7268

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026