An Exploratory Study of Senescence Associated Glycoprotein (SAGP) in Idiopathic Pulmonary Fibrosis: A Cross Sectional Study Using Blood and Lung Tissue Samples

Exploratory Investigation of Senescence-Associated Glycoprotein (SAGP) Expression in Idiopathic Pulmonary Fibrosis: A Cross-Sectional Observational Study Using Peripheral Blood and Lung Tissue - SAGP-IPF Cross-Sectional Study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000060899

Enrollment

Registered

2026-04-01

Start date

2026-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Idiopathic pulmonary fibrosis

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Individuals aged 16 years or older at the time of obtaining informed consent. 2. Individuals who are suspected of having or have been diagnosed with idiopathic pulmonary fibrosis. 3. Individuals who have received sufficient explanation about the study and have provided written informed consent of their own free will.

Exclusion criteria

Exclusion criteria: Individuals who are judged by the principal investigator to be inappropriate for participation in this study.

Design outcomes

Primary

Measure	Time frame
Examination of senescence-associated glycoprotein (SAGP) expression in lung tissue assessed in patients undergoing diagnostic lung biopsy	—

Secondary

Measure	Time frame
Circulating SAGP level at the time of sample collection after informed consent Association between circulating SAGP levels and pulmonary function parameters (VC, FVC, DLco) Association between circulating SAGP levels and established biomarkers (KL-6, SP-D, proBNP) Association between circulating SAGP levels and DNA methylation profiles	—

Countries

Japan

Contacts

Public ContactYusuke Joki

Juntendo University Hospital Department of Cardiovascular Biology and Medicine

yjyouki@juntendo.ac.jp03-3813-3111

Outcome results