Atopic dermatitis
Conditions
Interventions
None listed
Sponsors
The Jikei University School of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: All of the following criteria must be met. 1) Aged 12 years or older 2) Residing in Japan 3) Provided informed consent (and parental consent for minors) after reading the study description 4) Previously diagnosed with atopic dermatitis by a physician and meeting the abbreviated UK Working Party (UKWP) diagnostic criteria for AD (by self-report) 5) Experienced at least one day with particularly severe itch within the past 7 days
Exclusion criteria
Exclusion criteria: No specific medical or ethical exclusion criteria are applied.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Odds ratio (95% confidence interval) for association between wearing heat-generating undergarments and worsening of itch, comparing the index day (Day A: worst itch day within 7 days) with the reference day (Day A-7: same weekday one week prior), assessed by conditional logistic regression including season-stratified analysis | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) Mean difference in Worst Itch NRS (0-10) between Day A and Day A-7 2) Proportion of participants with MCID or greater worsening of itch on Day A vs. Day A-7 3) Effect of heat-generating undergarments after adjustment for same-day factors (sweating, exercise, air conditioning use, etc.) 4) Association between undergarment brand/fit and itch severity (exploratory) | — |
Countries
Japan
Contacts
Public ContactKenta Horimukai
Katsushika Medical Center, The Jikei University School of Medicine Department of Pediatrics
Outcome results
None listed