Oral lichen planus
Conditions
Interventions
Oral inulin supplementation. After a 2-week pre-observation period, participants randomized to the inulin group will receive 4 g of inulin per sachet, taken twice daily (e.g., after breakfast and dinn
Sponsors
Kyushu University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients diagnosed with oral lichen planus by a dentist 2. Male and female patients aged 18 years or older 3. Individuals who have received sufficient explanation about the study, fully understood its contents, and provided written informed consent of their own free will
Exclusion criteria
Exclusion criteria: 1. Individuals who have used antibiotics within the past 3 months 2. Individuals with a history of hospitalization within the past 3 months 3. Individuals who refuse to participate in this study 4. Pregnant women or women who may be pregnant 5. Individuals with food allergies to inulin or plants of the Asteraceae (Compositae) family, which are the source materials of inulin 6. Any other individuals deemed inappropriate as study participants by the principal investigator Participants who receive antibiotics during the study period will also be excluded from the analysis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in the proportion of butyrate-producing bacteria in the fecal gut microbiota between baseline (before inulin intake) and the end of the 4-week inulin supplementation period. | — |
Countries
Japan
Contacts
Public ContactNaoki Kaneko
Kyushu University Section of Oral and Maxillofacial Surgery, Division of Maxillofacial Diagnostic and Surgical Science
Outcome results
None listed