A 3-Month Prospective Study of Combined Exercise and Nutritional Counseling in Hospital Staff: Effects on Liver Function, Body Composition, and Lifestyle
Conditions
Interventions
Exercise guidance using a YouTube playlist Dietary intervention by a registered dietitian Body composition assessment using InBody These components are combined to evaluate the effects of a 3-month
Sponsors
Okayama University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Eligible participants are in-hospital staff members of Shigei Hospital who wish to attend the staff-oriented fatty liver clinic and who meet at least one of the following criteria. Participants must receive a full explanation of the study and provide written informed consent based on sufficient understanding and voluntary agreement. Body mass index (BMI) >= 23 kg/m2 and waist circumference >= 94 cm in men or >= 80 cm in women. Fasting plasma glucose >= 100 mg/dL, HbA1c >= 5.7%, diagnosis of type 2 diabetes mellitus, or current use of antidiabetic medication. Blood pressure >= 135/85 mmHg or current use of antihypertensive medication. Triglycerides >= 150 mg/dL or current use of lipid-lowering medication. Low HDL cholesterol: <= 40 mg/dL in men or <= 50 mg/dL in women.
Exclusion criteria
Exclusion criteria: Age < 20 years or >= 65 years. Presence of liver cirrhosis, cardiovascular disease, malignant neoplasm, pregnancy, or severe limitations in physical activity.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary endpoint primary outcome Change in ALT Delta ALT Secondary endpoints secondary outcomes Changes in laboratory parameters liver function lipids glycemic indices renal function urinalysis AST gGTP HbA1c HDL C LDL C TG eGFR blood glucose urinalysis Changes in body composition and anthropometric measures InBody BIA body weight BMI skeletal muscle mass fat mass body fat percentage visceral fat level Changes in physical activity and dietary habits Estimated basal metabolic rate BMR IPAQ Short Form IPAQ Long Form International Physical Activity Questionnaire GPAQ Global Physical Activity Questionnaire Exercise habits questionnaire BDHQ Brief type Self administered Diet History Questionnaire | — |
Countries
Japan
Contacts
Public ContactMIWA KAWANAKA
Okayama University Department of Gastroenterology and Hepatology
Outcome results
None listed