Evaluation of the kukui nut oil (Aleurites moluccanus seed oil) for eyelash length in healthy adults

A prospective, randomized, double-blind, vehicle-controlled, within-subject (contralateral) study evaluating changes in eyelash length following topical application of kukui nut oil (Aleurites moluccanus seed oil) in healthy adults - Evaluation of changes in eyelash length following topical application of kukui nut oil

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000060798

Enrollment

Registered

2026-03-02

Start date

2025-01-07

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Interventions

Topical application of eyelash serum containing 0.1% kukui nut oil, applied twice daily for 4 weeks to the randomized eyelash side (left or right). Topical application of vehicle serum without activ

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1) Japanese women aged 20 to 49 at the time of consent acquisition 2) Individuals who perceive their eyelash length as average (neither extremely long nor extremely short) 3) Individuals who can agree not to use mascara, eyelash curlers, or false eyelashes during the trial period 4) Individuals who can agree not to undergo cosmetic procedures on their eyelashes, such as eyelash extensions or eyelash perms, during the trial period 5) Individuals not currently wearing false eyelashes, or who last wore false eyelashes at least 2 weeks prior 6) Individuals not currently wearing eyelash extensions, or who last had eyelash extensions applied at least 4 weeks prior

Exclusion criteria

Exclusion criteria: 1) Individuals with permanent makeup applied to the eyeliner area 2) Individuals who are pregnant, may be pregnant, or are breastfeeding 3) Individuals who may exhibit allergic reactions to any component of the test product 4) Individuals participating in other clinical trials 5) Individuals taking supplements or medications that may affect the efficacy of the test product (e.g., glaucoma medications, eyelash hypotrichosis treatments) 6) Individuals currently receiving treatment at a dermatology or ophthalmology clinic 7) Individuals suspected of having, or with a history of, severe digestive disorders, liver disease, kidney disease, cardiovascular disease, blood disorders, endocrine disorders, or malignant neoplasms

Design outcomes

Primary

Measure	Time frame
Change in eyelash length	—

Secondary

Measure	Time frame
Subjects' subjective evaluation of eyelash growth effects	—

Countries

Japan

Contacts

Public ContactTakeshi Hara

Mandom Corporation Advanced Technology Institute

takeshi.hara@mandom.com06-6105-5785

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026