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Predicting Pediatric Airway Morbidity with Pre-extubation Fiberoptic Laryngoscopy

Predicting Pediatric Airway Morbidity with Pre-extubation Fiberoptic Laryngoscopy - P-AMAFL Study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000060787
Enrollment
116
Registered
2026-02-28
Start date
2026-03-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

post-extubation laryngeal edema

Interventions

Laryngeal fiberoptic examination will be performed at the time of extubation. Two physicians will independently assess the pre-extubation laryngeal fiberoptic images using recorded videos that have be

Sponsors

Hyogo Prefectural Amagasaki General Medical Center
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Oral or nasal endotracheal intubation (either is acceptable). 2. Aged 18 years or younger. 3. Use of a cuffed endotracheal tube. 4. Written informed consent has been obtained from the patient and/or a legally authorized representative (the patient's parent/guardian). 5. Extubation is planned between 08:30 and 17:00. (To ensure assessment quality, the procedure will be performed only during daytime hours so that multiple staff members can attend.) 6. The department conference has determined that performing laryngeal fiberoptic examination is appropriate.

Exclusion criteria

Exclusion criteria: 1. Unplanned extubation (because the examination cannot be performed). 2. The examination is judged to carry a high risk due to underlying conditions or other clinical factors (including situations in which transnasal insertion is difficult, such as after head and neck surgery). 3. History of allergy to local anesthetics.

Design outcomes

Primary

MeasureTime frame
Presence of post-extubation stridor (PES) within 60 minutes after extubation

Secondary

MeasureTime frame
National Paediatric Early Warning System (NPEWS) score within 60 minutes after extubation Presence of chest retractions within 60 minutes after extubation Administration of systemic corticosteroids within 60 minutes after extubation Use of high-flow nasal cannula (HFNC) within 24 hours after extubation Use of noninvasive ventilation (NIV) within 24 hours after extubation Reintubation within 24 hours after extubation Procedure-related complications (e.g., nasal bleeding, oral bleeding)

Countries

Japan

Contacts

Public ContactKoji Kanno

Hyogo Prefectural Amagasaki General Medical Center Department of Pediatric Emergency and Critical Care Medicine

nemurisugitakan@gmail.com0664807000

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026