healthy volunteers
Conditions
Interventions
topical test product.The topical test product will be applied to one side of the face for 8 weeks.
The placebo product will be applied to the contralateral side of the face.
Sponsors
Rohto Pharmaceutical Co., Ltd.
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Subjects meeting all of the following criteria will be included: 1. Healthy Japanese females aged 30 to 60 years at the time of informed consent 2. Subjects who are able to understand the study procedures and provide written informed consent 3. Subjects who are able to use the investigational product as instructed during the study period 4. Subjects who have subjective awareness of facial redness
Exclusion criteria
Exclusion criteria: Subjects meeting any of the following criteria will be excluded: 1. Subjects with any dermatological condition at the study site or systemic condition that may affect study evaluation 2. Subjects with a history of medication use, medical treatment, or medical/cosmetic procedures that may affect the study results 3. Subjects with a history of severe hypersensitivity or allergy to drugs, cosmetics, or related products 4. Subjects who are pregnant, breastfeeding, or possibly pregnant 5. Subjects who are currently participating in another clinical trial or planning to participate in another clinical trial 6. Subjects who are likely to experience significant changes in living environment or external factors (e.g., ultraviolet exposure) during the study period that may affect the evaluation 7. Subjects who are unable to comply with study procedures or provide adequate cooperation 8. Subjects who are judged by the principal investigator to be unsuitable for participation for any reason
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in skin color parameters (L* and a* values) | — |
Countries
Japan
Contacts
Public ContactEiko Uno
Rohto Pharmaceutical Co., Ltd. Fundamental Technology Research Department
Outcome results
None listed