Study on Salivary Secretion During Induction of General Anesthesia and Its Impact on Dental Anesthesia and Oral Surgery Conditions

Clinical Significance of Salivary Secretion Changes During Induction of General Anesthesia: A Prospective Observational Study in Dental Anesthesia and Oral Surgery Settings - Dental Anesthesia and Salivary Secretion in Oral Surgery

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000060760

Enrollment

Registered

2026-03-01

Start date

2026-03-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients undergoing oral and maxillofacial surgery under general anesthesia

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who meet all of the following criteria will be included: 1. Patients scheduled for oral and maxillofacial surgery under general anesthesia 2. Age over 20 years 3. Written informed consent obtained after adequate explanation of the study

Exclusion criteria

Exclusion criteria: Patients meeting any of the following criteria will be excluded: 1. History of salivary gland surgery 2. History of radiation therapy to the head and neck region 3. Regular use of medications known to cause xerostomia 4. Persistent subjective symptoms of oral dryness 5. Severe hepatic or renal dysfunction 6. Patients deemed inappropriate for participation by the investigator

Design outcomes

Primary

Measure	Time frame
The primary outcome is the salivary flow rate during tracheal intubation under induction of general anesthesia. Salivary flow rate will be calculated by measuring the weight of saliva collected through routine oral and pharyngeal suction during anesthesia induction and dividing it by the collection time to obtain secretion volume per unit time.	—

Countries

Japan

Contacts

Public ContactShota Tsukimoto

Nagasaki University Hospital Department of dental anesthesiology

s-tsukimoto@nagasaki-u.ac.jp095-821-7714

Outcome results